See PubMed for links to the full-text papers
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FULL LENGTH ARTICLES – PUBLISHED OR IN PRESS
140. Malaspina S, Taimen P, Kallajoki M, Oikonen V, Kuisma A, Ettala O, Mattila K, Boström PJ, Minn H, Kalliokoski K, Postema EJ, Miller MP, Scheinin M. Uptake of 18 F-rhPSMA-7.3 in Positron Emission Tomography Imaging of Prostate Cancer: A Phase 1 Proof-of-Concept Study. Cancer Biother Radiopharm. in press: , 2021. [IF ]
139. Garthwaite T, Sjöros T, Koivumäki M, Laine S, Vähä-Ypyä H, Saarenhovi M, Kallio P, Löyttyniemi E, Sievänen H, Houttu N, Laitinen K, Kalliokoski K, Vasankari T, Knuuti J, Heinonen I.. Standing is associated with insulin sensitivity in adults with metabolic syndrome. J Sci Med Sport. 24: 1255-1260, 2021. [IF ]
138. Haapala EA, Sjöros T, Laine S, Garthwaite T, Kallio P, Saarenhovi M, Vähä-Ypyä H, Löyttyniemi E, Sievänen H, Houttu N, Laitinen K, Kalliokoski K, Knuuti J, Vasankari T, Heinonen IHA.. Association between cardiorespiratory fitness and metabolic health in overweight and obese adults. J Sports Med Phys Fitness. in press: , 2021. [IF ]
137. Kantonen T, Pekkarinen L, Karjalainen T, Bucci M, Kalliokoski K, Haaparanta-Solin M, Aarnio R, Dickens AM, von Eyken A, Laitinen K, Houttu N, Kirjavainen AK, Helin S, Hirvonen J, Rönnemaa T, Nuutila P, Nummenmaa L. Obesity risk is associated with altered cerebral glucose metabolism and decreased µ-opioid and CB 1 receptor availability. Int J Obes. in press: , 2021. [IF ]
136. Kantonen T, Karjalainen T, Pekkarinen L, Isojärvi J, Kalliokoski K, Kaasinen V, Hirvonen J, Nuutila P, Nummenmaa L. Cerebral µ-opioid and CB 1 receptor systems have distinct roles in human feeding behavior. Transl Psychiatry. 11: 442, 2021. [IF ]
135. Sjöros T, Vähä-Ypyä H, Laine S, Garthwaite T, Löyttyniemi E, Sievänen H, Kalliokoski KK, Knuuti J, Vasankari T, Heinonen IHA. Influence of the Duration and Timing of Data Collection on Accelerometer-Measured Physical Activity, Sedentary Time and Associated Insulin Resistance. Int J Environ Res Public Health. 18: 4950, 2021. [IF 3.39]
134. Malaspina S, Oikonen V, Kuisma A, Ettala O, Mattila K, Boström PJ, Minn H, Kalliokoski K, Postema EJ, Miller MP, Scheinin M. Kinetic analysis and optimisation of 18F-rhPSMA-7.3 PET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 48: 3723-3731, 2021. [IF 9.236]
133. Sun L, Tang J, Liljenbäck H, Honkaniemi A, Virta J, Isojärvi J, Karjalainen T, Kantonen T, Nuutila P, Hietala J, Kaasinen V, Kalliokoski K, Hirvonen J, Scheinin H, Helin S, Eerola K, Savontaus E, Yatkin E, Rinne JO, Roivainen A, Nummenmaa L. Seasonal Variation in the Brain ?-Opioid Receptor Availability. J Neurosci. 41: 1265-1273, 2021. [IF 6.167]
132. Laine S, Högel H, Ishizu T, Toivanen J, Yli-Karjanmaa M, Grönroos TJ, Rantala J, Mäkelä R, Hannukainen JC, Kalliokoski KK, Heinonen I. Effects of Different Exercise Training Protocols on Gene Expression of Rac1 and PAK1 in Healthy Rat Fast- and Slow-Type Muscles. Front Physiol. 11: 584661, 2020. [IF 4.566]
131. Sjöros T, Vähä-Ypyä H, Laine S, Garthwaite T, Lahesmaa M, Laurila SM, Latva- Rasku A, Savolainen A, Miikkulainen A, Löyttyniemi E, Sievänen H, Kalliokoski KK, Knuuti J, Vasankari T, Heinonen IHA. Both sedentary time and physical activity are associated with cardiometabolic health in overweight adults in a 1 month accelerometer measurement. Sci Rep. 10: 20578, 2020. [IF 4.379]
130. Middelbeek R, Motiani P, Brandt N, Nigro P, Zheng J, Virtanen K, Kalliokoski K, Hannukainen J, Goodyear L. Exercise Intensity Regulates Cytokine and Klotho Responses in Men. Nutr Diabetes. 11: 5, 2021. [IF 5.097]
129. Tolvanen T, Kalliokoski K, Malaspina S, Kuisma A, Lahdenpohja S, Postema EJ, Miller MP, Scheinin M. Safety, biodistribution and radiation dosimetry of 18F-rhPSMA-7.3 in healthy adult volunteers. J Nucl Med. 62: 679-684, 2021. [IF 10.057]
128. Soppi E, Knuuti J, Kalliokoski K. Effects of two different pressure relieving support surfaces on the pathophysiological cascade of pressure ulcer development – a positron emission tomography (PET). J Wound Care. 30: 54-62, 2021. [IF 2.072]
127. Dadson P, Rebelos E, Honka H, Juárez-Orozco LE, Kalliokoski KK, Iozzo P, Teuho J, Salminen P, Pihlajamäki J, Hannukainen JC, Nuutila P. Change in abdominal, but not femoral subcutaneous fat CT-radiodensity is associated with improved metabolic profile after bariatric surgery. Nutr Metab Cardiovasc Dis. 30: 2363-2371, 2020. [IF 4.222]
126. Honkala SM, Motiani P, Kivelä R, Hemanthakumar KA, Tolvanen E, Motiani KK, Eskelinen JJ, Virtanen KA, Kemppainen J, Heiskanen MA, Löyttyniemi E, Nuutila P, Kalliokoski KK, Hannukainen JC. Exercise training improves adipose tissue metabolism and vasculature regardless of baseline glucose tolerance and sex. BMJ Open Diabetes Res Care. 8: e000830, 2020. [IF 3.388]
125. Ojala R, Motiani KK, Ivaska KK, Arponen M, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Heiskanen MA, U-Din M, Nuutila P, Kalliokoski KK, Hannukainen JC. Bone marrow metabolism is impaired in insulin resistance and improves after exercise training. J Clin Endocrinol Metab. 105: e4290-e4303, 2020. [IF 5.958]
124. Nummenmaa L, Karjalainen T, Isojärvi J, Kantonen T, Tuisku J, Kaasinen V, Joutsa J, Nuutila P, Kalliokoski K, Hirvonen J, Hietala J, Rinne J. Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety. Neuropsychopharmacology. 45: 1953-1959, 2020. [IF 7.853]
123. Kantonen T, Karjalainen T, Isojärvi J, Nuutila P, Tuisku J, Rinne J, Hietala J, Kaasinen V, Kalliokoski K, Scheinin H, Hirvonen J, Vehtari A, Nummenmaa L. Interindividual variability and lateralization of μ-opioid receptors in the human brain. Neuroimage. 217: 116922, 2020. [IF 6.556]
122. Mawhinney C, Heinonen I, Low DA, Han C, Jones H, Kalliokoski KK, Kirjavainen A, Kemppainen J, Di Salvo V, Weston M, Cable T, Gregson W. Changes in quadriceps femoris muscle perfusion following different degrees of cold-water immersion. J Appl Physiol. 128: 1392-1401, 2020. [IF 3.531]
121. Klén R, Honka MJ, Hannukainen JC, Huovinen V, Bucci M, Latva-Rasku A, Venäläinen MS, Kalliokoski KK, Virtanen KA, Lautamäki R, Iozzo P, Elo LL, Nuutila P. Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling. J Endocr Soc. 4: bvaa026, 2020. [IF ]
120. Motiani KK, Carmen Collado M, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Salminen S, Nuutila P, Kalliokoski KK, Hannukainen JC. Exercise training modulates gut microbiota profile and improves endotoxemia. Med Sci Sports Exerc. 52: 94-104, 2020. [IF 5.411]
119. Kudomi N, Kalliokoski KK, Oikonen VJ, Han C, Kemppainen J, Sipilä HT, Knuuti J, Heinonen IHA. Myocardial Blood Flow and Metabolic Rate of Oxygen Measurement in the Right and Left Ventricles at Rest and During Exercise Using 15O-Labeled Compounds and PET. Front Physiol. 19: 741, 2019. [IF 4.566]
119. Motiani KK, Savolainen A, Toivanen J, Eskelinen JJ, Yli-Karjanmaa M, Virtanen KA, Saunavaara V, Heiskanen M, Parkkola R, Haaparanta-Solin M, Solin O, Savisto N, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. Effects of short-term sprint interval and moderate-intensity continuous training on liver fat, lipoprotein profile and substrate uptake: a randomized trial. J Appl Physiol. in press. [IF 3.351]
118. Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Nigro P, Ryan RE, Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM, Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S, Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ. TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism. Nat Metab. 1: 291-303, 2019. [IF new journal, no IF yet]
117. Sjöros T, Saunavaara V, Löyttyniemi E, Koivumäki M, Heinonen IHA, Eskelinen JJ, Virtanen KA, Hannukainen JC, Kalliokoski KK. Intramyocellular lipid accumulation after sprint interval and moderate-intensity continuous training in healthy and diabetic subjects. Physiol Rep. 7: e13980, 2019. [IF new journal, no IF yet]
116. Laaksonen MS, Kyröläinen H, Kemppainen J, Knuuti J, Kalliokoski K. Muscle free fatty-acid uptake associates to mechanical efficiency during exercise in humans. Front Physiol. 9: 1171, 2018. [IF 4.134]
115. Heinonen I, Kemppainen J, Fujimoto T, Knuuti J, Kalliokoski K. Increase of glucose uptake in human bone marrow with increasing exercise intensity. Int J Sport Nutr Exerc Metab. in press. [IF 2.49]
114. Saanijoki T, Nummenmaa L, Tuulari J, Tuominen L, Arponen E, Kalliokoski K, Hirvonen J. Aerobic exercise modulates anticipatory reward processing via the μ-opioid receptor system. Hum Brain Mapp. 39: 3972-3983, 2018. [IF 4.53]
113. Heiskanen1 MA, Motiani KK, Mari A, Saunavaara V, Eskelinen JJ, Virtanen KA, Koivumäki M, Löyttyniemi E, Nuutila P, Kalliokoski KK, Hannukainen JC. Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: A randomized controlled trial. Diabetologia. 61: 1817-1828, 2018. [IF 6.08]
112. Honka M-J, Hyypiä A, Bucci M, Virtanen K, Hannukainen JC, Kalliokoski KK, Nuutila P. Insulin Stimulated Glucose Uptake in Skeletal Muscle, Adipose Tissue and Liver: A Positron Emission Tomography Study. Eur J Endocrinol. 178: 523-531, 2018. [IF 4.101]
111. Nummenmaa L, Saanijoki T, Tuominen L, Hirvonen J, Tuulari J, Nuutila P, Kalliokoski K. Mu-opioid receptor system mediates visual reward processing in humans. Nat Commun. 9: 1500, 2018. [IF 12.124]
110. Dadson P, Hannukainen JC, U Din M, Kalliokoski KK, Iozzo P, Pihlajamäki J, Karlsson HK, Parkkola R, Salminen P, Virtanen KA, Nuutila P. Brown adipose tissue lipid metabolism in morbid obesity: the effect of bariatric surgery-induced weight loss. Diabetes Obes Metab, 20: 1280-1288, 2018. [IF 6.715]
109. Heinonen I, Boushel R, Hellsten Y, Kalliokoski K. Regulation of bone blood flow in humans: The role of nitric oxide, prostaglandins, and adenosine. Scand J Med Sci Sports, 28: 1552-1558, 2018. [IF 3.331]
108. Honkala SM, Johansson J, Motiani KK, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. Short-term interval training alters brain glucose metabolism in subjects with insulin resistance. J Cereb Blood Flow Metab, in press [IF 5.081]
107. Saanijoki T, Nummenmaa L, Koivumäki M, Löyttyniemi E, Kalliokoski KK, Hannukainen JC. Affective adaptation to repeated SIT and MICT protocols in insulin resistant subjects. Med Sci Sports Exerc. 50:18-27, 2018. [IF 4.141]
106. Heiskanen MA, Sjöros T, Heinonen IH, Löyttyniemi E, Koivumäki M, Motiani KK, Eskelinen JJ, Virtanen K, Knuuti J, Hannukainen JC, Kalliokoski KK. Sprint interval training decreases left-ventricular glucose uptake compared to moderate-intensity continuous training in subjects with type 2 diabetes or prediabetes. Sci Rep. 7: 10531, 2017. [IF 4.259]
105. Saanijoki T, Tuominen L, Tuulari JJ, Nummenmaa L, Arponen E, Kalliokoski K, Hirvonen J. Opioid Release after High-Intensity Interval Training in Healthy Human Subjects. Neuropsychopharmacology, 43:246-254, 2018. [IF 6.403]
104. Dadson P, Ferrannini E, Landini L, Hannukainen JC, Kalliokoski KK, Vaittinen M, Honka H, Karlsson HK, Tuulari JJ, Soinio M, Salminen P, Parkkola R, Pihlajamäki J, Iozzo P, Nuutila P. Fatty acid uptake and blood flow in adipose tissue compartments of morbidly obese subjects with or without type 2 diabetes: effects of bariatric surgery. Am J Physiol Endocrinol Metab, 313:E175-E182, 2017. [IF 3.825]
103. Heinonen I, Saltin B, Hellsten Y, Kalliokoski KK. The effect of nitric oxide synthase inhibition with and without inhibition of prostaglandins on blood flow in different human skeletal muscles. Eur J Appl Physiol, 117: 1175-1180, 2017. [IF 2.328]
102. Motiani P, Virtanen KA, Motiani KK, Eskelinen JJ, Middelbeek RJ, Goodyear LJ, Savolainen AM, Kemppainen J, Jensen J, U Din M, Saunavaara V, Parkkola R, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. Decreased insulin-stimulated brown adipose tissue glucose uptake after short term exercise training in healthy middle aged men. Diabetes Obes Metab, 19:1379-1388, 2018. [IF 6.198]
101. Sjöros TJ, Heiskanen MA, Motiani KK, Löyttyniemi E, Eskelinen JJ, Virtanen KA, Savisto NJ, Solin O, Hannukainen JC, Kalliokoski KK. Increased insulin-stimulated glucose uptake in both leg and arm muscles after sprint interval and moderate intensity training in subjects with Type 2 Diabetes or Prediabetes. Scand J Med Sci Sports. 28:77-87, 2018. [IF 3.025]
100. Motiani KK, Savolainen A, Eskelinen JJ, Toivanen J, Ishizu T, Yli-Karjanmaa M, Virtanen KA, Parkkola R, Kapanen J, Grönroos T, Haaparanta-Solin M, Solin O, Savisto N, Ahotupa M, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC. Two weeks of moderate intensity continuous training, but not high intensity interval training increases insulin-stimulated intestinal glucose uptake. J Appl Physiol. 122: 1188-1197, 2017. [IF 3.004]
99. Honkala SM, Motiani KK, Eskelinen JJ, Savolainen A, Saunavaara V, Virtanen KA, Löyttyniemi E, Kapanen J, Knuuti J, Kalliokoski KK, Hannukainen JC. Exercise training reduces intrathoracic fat regardless of defective glucose tolerance. Med Sci Sports Exerc, 49: 1313-1322, 2017. [IF 4.041]
98. Heinonen IHA, Boushel R, Kalliokoski K. The circulatory and metabolic responses to hypoxia in humans – with special reference to adipose tissue physiology and obesity. Front Endocrinol. 7:116, 2016. [IF, no IF yet]
97. Eskelinen JJ, Heinonen I, Löyttyniemi E, Hakala J, Heiskanen M, Motiani K, Virtanen K, Pärkkä J, Knuuti J, Hannukainen JC, Kalliokoski KK. Left-ventricular vascular and metabolic adaptations to high-intensity interval and moderate intensity continuous training. A randomized trial in healthy middle-aged men. J Physiol. 594:7127-7140, 2016. [IF 4.731]
96. Heiskanen MA, Leskinen T, Heinonen I, Loyttyniemi E, Eskelinen JJ, Virtanen K, Hannukainen JC, Kalliokoski KK. Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men. Am J Physiol Heart Circ Physiol. 311:H667-H675, 2016. [IF 3.324]
95. Masood T, Kalliokoski K, Bojsen-Moller J, Finni T. Muscle-tendon glucose uptake in Achilles tendon rupture and tendinopathy before and after eccentric rehabilitation: Comparative case reports. Phys Ther Sport, 21: 14-19, 2016. [IF 1.575]
94. Haavisto M, Saraste A, Pirila L, Hannukainen JC, Kalliokoski KK, Kirjavainen A, Kemppainen J, Mottonen T, Knuuti J, Yli-Kerttula T, Roivainen A. Influence of triple disease modifying anti-rheumatic drug therapy on carotid artery inflammation in drug-naive patients with recent onset of rheumatoid arthritis. Rheumatology, 55:1777-1785, 2016. [IF 4.524]
93. Karjalainen T, Tuominen L, Manninen S, Kalliokoski KK, Nuutila P, Jaaskelainen IP, Hari R, Sams M, Nummenmaa L. Behavioural activation system sensitivity is associated with cerebral mu-opioid receptor availability. Soc Cogn Affect Neurosci. 11:1310-1316, 2016. [IF 5.101]
92. Heiskanen MA, Leskinen T, Eskelinen JJ, Heinonen IH, Loyttyniemi E, Virtanen K, Parkka JP, Hannukainen JC, Kalliokoski KK. Different Predictors of Right and Left Ventricular Metabolism in Healthy Middle-Aged Men. Front Physiol. 6: 389, 2015. [IF 4.031]
91. Kiviniemi AM, Tulppo MP, Eskelinen JJ, Savolainen AM, Kapanen J, Heinonen IH, Hautala AJ, Hannukainen JC, Kalliokoski KK. Autonomic Function Predicts Fitness Response to Short-Term High-Intensity Interval Training. Int J Sports Med. 36: 915-921, 2015. [IF 2.528]
90. Saanijoki T, Nummenmaa L, Eskelinen JJ, Savolainen AM, Vahlberg T, Kalliokoski KK, Hannukainen JC. Affective Responses to Repeated Sessions of High-Intensity Interval Training. Med Sci Sports Exerc. 47: 2604-2611, 2015. [IF 4.041]
89. Nummenmaa L, Manninen S, Tuominen L, Hirvonen J, Kalliokoski KK, Nuutila P, Jaaskelainen IP, Hari R, Dunbar RI, Sams M. Adult attachment style is associated with cerebral mu-opioid receptor availability in humans. Hum Brain Mapp. 36: 3621-3628, 2015. [IF 4.962]
88. Kindred JH, Kalliokoski KK, Bojsen-Moller J, Rudroff T. Regional differences of [(18)F]-FDG uptake within the brain during fatiguing muscle contractions. Brain Behav. 5: e00319, 2015. [IF 2.128]
87. Eskelinen JJ, Heinonen I, Loyttyniemi E, Saunavaara V, Kirjavainen A, Virtanen KA, Hannukainen JC, Kalliokoski KK. Muscle-specific glucose and free fatty acid uptake after sprint interval and moderate-intensity training in healthy middle-aged men. J Appl Physiol. 118: 1172-1180, 2015. [IF 3.004]
86. Rudroff T, Kindred JH, Kalliokoski KK. [18F]-FDG positron emission tomography–an established clinical tool opening a new window into exercise physiology. J Appl Physiol. 118: 1181-1190, 2015. [IF 3.004]
85. Kindred JH, Tuulari JJ, Bucci M, Kalliokoski KK, Rudroff T. Walking Speed and Brain Glucose Uptake are Uncoupled in Patients with Multiple Sclerosis. Front Hum Neurosci. 9: 84, 2015. [IF 3.634]
84. Heinonen I, Koga S, Kalliokoski KK, Musch TI, Poole DC. Heterogeneity of Muscle Blood Flow and Metabolism: Influence of Exercise, Aging, and Disease States. Exerc Sport Sci Rev. 43: 117-124, 2015. [IF 4.451]
83. Kauhanen L, Murtola L-M, Heimonen J, Leskinen T, Kalliokoski K, Raivo E, Salakoski S, Salanterä S. Documentation of the Clinical Phase of the Cardiac Rehabilitation Process in a Finnish University Hospital District. Communications in Computer and Information Science, 450:57-67, 2014.
82. Heinonen I, Kalliokoski KK, Hannukainen JC, Duncker DJ, Nuutila P, Knuuti J. Organ-specific physiological responses to acute physical exercise and long-term training in humans. Physiology 29: 421-436, 2014. [IF 6.541]
81. Bucci M, Karmi AC, Iozzo P, Fielding BA, Viljanen A, Badeau RM, Borra R, Saunavaara V, Pham T, Hannukainen JC, Kalliokoski K, Haaparanta-Solin M, Viljanen T, Parkkola R, Frayn KN, Nuutila P. Enhanced fatty acid uptake in visceral adipose tissue is not reversed by weight loss in obese individuals with the metabolic syndrome. Diabetologia. 58: 158-164, 2015. [IF 6.206]
80. Rudroff T, Kindred JH, Benson JM, Tracy BL, Kalliokoski KK. Greater glucose uptake heterogeneity in knee muscles of old compared to young men during isometric contractions detected by [(18)F]-FDG PET/CT. Front Physiol. 5: 198, 2014. [IF 4.031]
79. Heinonen I, Kudomi N, Kemppainen J, Kiviniemi A, Noponen T, Luotolahti M, Luoto P, Oikonen V, Sipila HT, Kopra J, Mononen I, Duncker DJ, Knuuti J, Kalliokoski KK. Myocardial blood flow and its transit time, oxygen utilization, and efficiency of highly endurance-trained human heart. Basic Res Cardiol. 109: 413, 2014. [IF 6.008]
78. Masood T, Kalliokoski K, Magnusson SP, Bojsen-Moller J, Finni T. Effects of 12-wk eccentric calf muscle training on muscle-tendon glucose uptake and SEMG in patients with chronic Achilles tendon pain. J Appl Physiol. 117: 105-111, 2014. [IF 3.004]
77. Heinonen I, Kemppainen J, Kaskinoro K, Knuuti J, Boushel R, Kalliokoski KK. Capacity and hypoxic response of subcutaneous adipose tissue blood flow in humans. Circ J. 78: 1501-1506, 2014. [IF 4.124]
76. Masood T, Bojsen-Moller J, Kalliokoski KK, Kirjavainen A, Aarimaa V, Peter MS, Finni T. Differential contributions of ankle plantarflexors during submaximal isometric muscle action: a PET and EMG study. J Electromyogr Kinesiol. 24: 367-374, 2014. [IF 1.53]
75. Masood T, Kalliokoski K, Bojsen-Moller J, Magnusson SP, Finni T. Plantarflexor muscle function in healthy and chronic Achilles tendon pain subjects evaluated by the use of EMG and PET imaging. Clin Biomech. 29: 564-570, 2014. [IF 1.636]
74. Kiviniemi AM, Tulppo MP, Eskelinen JJ, Savolainen AM, Kapanen J, Heinonen IH, Huikuri HV, Hannukainen JC, Kalliokoski KK. Cardiac autonomic function and high-intensity interval training in middle-age men. Med Sci Sports Exerc. 46: 1960-1967, 2014. [IF 4.041]
73. Laaksonen MS, Heinonen I, Luotolahti M, Knuuti J, Kalliokoski KK. VO(2peak), myocardial hypertrophy, and myocardial blood flow in endurance-trained men. Med Sci Sports Exerc. 46: 1498-1505, 2014. [IF 4.041]
72. Rudroff T, Weissman JA, Bucci M, Seppanen M, Kaskinoro K, Heinonen I, Kalliokoski KK. Positron emission tomography detects greater blood flow and less blood flow heterogeneity in the exercising skeletal muscles of old compared with young men during fatiguing contractions. J Physiol. 592: 337-349, 2014. [IF 4.731]
71. Heinonen I, Saltin B, Kemppainen J, Nuutila P, Knuuti J, Kalliokoski K, Hellsten Y. Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle. Nutr Metab. 10: 43, 2013. [IF 3.28]
70. Heinonen I, Wendelin-Saarenhovi M, Kaskinoro K, Knuuti J, Scheinin M, Kalliokoski KK. Inhibition of alpha-adrenergic tone disturbs the distribution of blood flow in the exercising human limb. Am J Physiol Heart Circ Physiol. 305: H163-H172, 2013. [IF 3.324]
69. Sperlich B, Born DP, Kaskinoro K, Kalliokoski KK, Laaksonen MS. Squeezing the muscle: compression clothing and muscle metabolism during recovery from high intensity exercise. PLoS One. 8: e60923, 2013. [IF 3.057]
68. Laaksonen MS, Kemppainen J, Kyrolainen H, Knuuti J, Nuutila P, Kalliokoski KK. Regional differences in blood flow, glucose uptake and fatty acid uptake within quadriceps femoris muscle during dynamic knee-extension exercise. Eur J Appl Physiol. 113: 1775-1782, 2013. [IF 2.328]
67. Rudroff T, Kalliokoski KK, Block DE, Gould JR, Klingensmith WC, Enoka RM. PET/CT imaging of age- and task-associated differences in muscle activity during fatiguing contractions. J Appl Physiol. 114: 1211-1219, 2013. [IF 3.004]
66. Heinonen I, Nesterov SV, Kemppainen J, Fujimoto T, Knuuti J, Kalliokoski KK. Increasing exercise intensity reduces heterogeneity of glucose uptake in human skeletal muscles. PLoS One. 7: e52191, 2012. [IF 3.057]
65. Heinonen I, Kemppainen J, Kaskinoro K, Langberg H, Knuuti J, Boushel R, Kjaer M, Kalliokoski KK. Bone blood flow and metabolism in humans: effect of muscular exercise and other physiological perturbations. J Bone Miner Res. 28: 1068-1074, 2013. [IF 5.622]
64. Heinonen I, Savolainen AM, Han C, Kemppainen J, Oikonen V, Luotolahti M, Duncker DJ, Merkus D, Knuuti J, Kalliokoski KK. Pulmonary blood flow and its distribution in highly trained endurance athletes and healthy control subjects. J Appl Physiol. 114: 329-334, 2013. [IF 3.004]
63. Heinonen I, Duncker DJ, Knuuti J, Kalliokoski KK. The effect of acute exercise with increasing workloads on inactive muscle blood flow and its heterogeneity in humans. Eur J Appl Physiol. 112: 3503-3509, 2012. [IF 2.328]
62. Heinonen I, Bucci M, Kemppainen J, Knuuti J, Nuutila P, Boushel R, Kalliokoski KK. Regulation of subcutaneous adipose tissue blood flow during exercise in humans. J Appl Physiol. 112: 1059-1063, 2012. [IF 3.004]
61. Heinonen I, Kemppainen J, Kaskinoro K, Peltonen JE, Sipila HT, Nuutila P, Knuuti J, Boushel R, Kalliokoski KK. Effects of adenosine, exercise, and moderate acute hypoxia on energy substrate utilization of human skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 302: R385-R390, 2012. [IF 3.168]
60. Kalliokoski KK, Boushel R, Langberg H, Scheede-Bergdahl C, Ryberg AK, Dossing S, Kjaer A, Kjaer M. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise. Front Physiol. 2: 75, 2011. [IF 4.031]
59. Heinonen I, Brothers RM, Kemppainen J, Knuuti J, Kalliokoski KK, Crandall CG. Local heating, but not indirect whole body heating, increases human skeletal muscle blood flow. J Appl Physiol. 111: 818-824, 2011. [IF 3.004]
58. Heinonen I, Saltin B, Kemppainen J, Sipila HT, Oikonen V, Nuutila P, Knuuti J, Kalliokoski K, Hellsten Y. Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a pet study with nitric oxide and cyclooxygenase inhibition. Am J Physiol Heart Circ Physiol. 300: H1510-H1517, 2011. [IF 3.324]
57. Hannukainen JC, Borra R, Linderborg K, Kallio H, Kiss J, Lepomaki V, Kalliokoski KK, Kujala UM, Kaprio J, Heinonen OJ, Komu M, Parkkola R, Ahotupa M, Lehtimaki T, Huupponen R, Iozzo P, Nuutila P. Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity. J Hepatol. 54: 545-552, 2011. [IF 10.59]
56. Bojsen-Moller J, Losnegard T, Kemppainen J, Viljanen T, Kalliokoski KK, Hallen J. Muscle use during double poling evaluated by positron emission tomography. J Appl Physiol. 109: 1895-1903, 2010. [IF 3.004]
55. Bojsen-Moller J, Schwartz S, Kalliokoski KK, Finni T, Magnusson SP. Intermuscular force transmission between human plantarflexor muscles in vivo. J Appl Physiol. 109: 1608-1618, 2010. [IF 3.004]
54. Schrey A, Kinnunen I, Kalliokoski K, Minn H, Grenman R, Vahlberg T, Niemi T, Suominen E, Aitasalo K. Perfusion in free breast reconstruction flap zones assessed with positron emission tomography. Microsurgery. 30: 430-436, 2010. [IF 2.054]
53. Laaksonen MS, Bjorklund G, Heinonen I, Kemppainen J, Knuuti J, Kyrolainen H, Kalliokoski KK. Perfusion heterogeneity does not explain excess muscle oxygen uptake during variable intensity exercise. Clin Physiol Funct Imaging. 30: 241-249, 2010. [IF 1.869]
52. Heinonen IH, Kemppainen J, Kaskinoro K, Peltonen JE, Borra R, Lindroos M, Oikonen V, Nuutila P, Knuuti J, Boushel R, Kalliokoski KK. Regulation of human skeletal muscle perfusion and its heterogeneity during exercise in moderate hypoxia. Am J Physiol Regul Integr Comp Physiol. 299: R72-R79, 2010. [IF 3.168]
51. Heinonen I, Kemppainen J, Kaskinoro K, Peltonen JE, Borra R, Lindroos MM, Oikonen V, Nuutila P, Knuuti J, Hellsten Y, Boushel R, Kalliokoski KK. Comparison of exogenous adenosine and voluntary exercise on human skeletal muscle perfusion and perfusion heterogeneity. J Appl Physiol. 108: 378-386, 2010. [IF 3.004]
50. Hannukainen JC, Kalliokoski KK, Borra RJ, Viljanen AP, Janatuinen T, Kujala UM, Kaprio J, Heinonen OJ, Viljanen T, Haaparanta M, Iozzo P, Parkkola R, Nuutila P. Higher free fatty acid uptake in visceral than in abdominal subcutaneous fat tissue in men. Obesity (Silver Spring). 18: 261-265, 2010. [IF 3.614]
49. Margadan-Mendez M, Juslin A, Nesterov SV, Kalliokoski K, Knuuti J, Ruotsalainen U. ICA based automatic segmentation of dynamic H(2)(15)O cardiac PET images. IEEE Trans Inf Technol Biomed. 14: 795-802, 2010. [IF 2.093]
48. Lindroos MM, Majamaa K, Tura A, Mari A, Kalliokoski KK, Taittonen MT, Iozzo P, Nuutila P. m.3243A>G mutation in mitochondrial DNA leads to decreased insulin sensitivity in skeletal muscle and to progressive beta-cell dysfunction. Diabetes. 58: 543-549, 2009. [IF 8.784]
47. Schrey A, Niemi T, Kinnunen I, Minn H, Vahlberg T, Kalliokoski K, Suominen E, Grenman R, Aitasalo K. The limitations of tissue-oxygen measurement and positron emission tomography as additional methods for postoperative breast reconstruction free-flap monitoring. J Plast Reconstr Aesthet Surg. 63: 314-321, 2010. [IF 1.743]
46. Mackey AL, Bojsen-Moller J, Qvortrup K, Langberg H, Suetta C, Kalliokoski KK, Kjaer M, Magnusson SP. Evidence of skeletal muscle damage following electrically stimulated isometric muscle contractions in humans. J Appl Physiol. 105: 1620-1627, 2008. [IF 3.004]
45. Heinonen I, Nesterov SV, Liukko K, Kemppainen J, Nagren K, Luotolahti M, Virsu P, Oikonen V, Nuutila P, Kujala UM, Kainulainen H, Boushel R, Knuuti J, Kalliokoski KK. Myocardial blood flow and adenosine A2A receptor density in endurance athletes and untrained men. J Physiol. 586: 5193-5202, 2008. [IF 4.731]
44. Heinonen I, Nesterov SV, Kemppainen J, Nuutila P, Knuuti J, Laitio R, Kjaer M, Boushel R, Kalliokoski KK. Role of adenosine in regulating the heterogeneity of skeletal muscle blood flow during exercise in humans. J Appl Physiol. 103: 2042-2048, 2007. [IF 3.004]
43. Kalliokoski KK, Bojsen-Moller J, Seppanen M, Johansson J, Kjaer M, Teras M, Magnusson SP. Contraction-induced [18F]-fluoro-deoxy-glucose uptake can be measured in human calf muscle using high-resolution PET. Clin Physiol Funct Imaging. 27: 239-241, 2007. [IF 1.869]
42. Knuuti J, Kalliokoski R, Janatuinen T, Hannukainen J, Kalliokoski KK, Koskenvuo J, Lundt S. Effect of estradiol-drospirenone hormone treatment on myocardial perfusion reserve in postmenopausal women with angina pectoris. Am J Cardiol. 99: 1648-1652, 2007. [IF 3.154]
41. Laaksonen MS, Kalliokoski KK, Luotolahti M, Kemppainen J, Teras M, Kyrolainen H, Nuutila P, Knuuti J. Myocardial perfusion during exercise in endurance-trained and untrained humans. Am J Physiol Regul Integr Comp Physiol. 293: R837-R843, 2007. [IF 3.168]
40. Hannukainen JC, Janatuinen T, Toikka JO, Jarvisalo MJ, Heinonen OJ, Kapanen J, Nagren K, Nuutila P, Kujala UM, Kaprio J, Knuuti J, Kalliokoski KK. Myocardial and peripheral vascular functional adaptation to exercise training. Scand J Med Sci Sports. 17: 139-147, 2007. [IF 3.025]
39. Juslin A, Lotjonen J, Nesterov SV, Kalliokoski K, Knuuti J, Ruotsalainen U. Alignment of 3-dimensional cardiac structures in O-15-labeled water PET emission images with mutual information. J Nucl Cardiol. 14: 82-91, 2007. [IF 2.929]
38. Hannukainen JC, Nuutila P, Borra R, Kaprio J, Kujala UM, Janatuinen T, Heinonen OJ, Kapanen J, Viljanen T, Haaparanta M, Ronnemaa T, Parkkola R, Knuuti J, Kalliokoski KK. Increased physical activity decreases hepatic free fatty acid uptake: a study in human monozygotic twins. J Physiol. 578: 347-358, 2007. [IF 4.731]
37. Kalliokoski KK, Scheede-Bergdahl C, Kjaer M, Boushel R. Muscle perfusion and metabolic heterogeneity: insights from noninvasive imaging techniques. Exerc Sport Sci Rev . 34: 164-170, 2006. [IF 4.451]
36. Kalliokoski RJ, Kalliokoski KK, Penttinen M, Kantola I, Leino A, Viikari JS, Simell O, Nuutila P, Raitakari OT. Structural and functional changes in peripheral vasculature of Fabry patients. J Inherit Metab Dis . 29: 660-666, 2006. [IF 3.541]
35. Hannukainen JC, Nuutila P, Kaprio J, Heinonen OJ, Kujala UM, Janatuinen T, Ronnemaa T, Kapanen J, Haaparanta-Solin M, Viljanen T, Knuuti J, Kalliokoski KK. Relationship between local perfusion and FFA uptake in human skeletal muscle-no effect of increased physical activity and aerobic fitness. J Appl Physiol. 101: 1303-1311, 2006. [IF 3.004]
34. Laaksonen MS, Kivela R, Kyrolainen H, Sipila S, Selanne H, Lautamaki R, Nuutila P, Knuuti J, Kalliokoski KK, Komi PV. Effects of exhaustive stretch-shortening cycle exercise on muscle blood flow during exercise. Acta Physiol. 186: 261-270, 2006. [IF 4.066]
33. Kalliokoski RJ, Kantola I, Kalliokoski KK, Engblom E, Sundell J, Hannukainen JC, Janatuinen T, Raitakari OT, Knuuti J, Penttinen M, Viikari J, Nuutila P. The effect of 12-month enzyme replacement therapy on myocardial perfusion in patients with Fabry disease. J Inherit Metab Dis . 29: 112-118, 2006. [IF 3.541]
32. Bojsen-Moller J, Kalliokoski KK, Seppanen M, Kjaer M, Magnusson SP. Low-intensity tensile loading increases intratendinous glucose uptake in the Achilles tendon. J Appl Physiol. 101: 196-201, 2006. [IF 3.004]
31. Kalliokoski KK, Langberg H, Ryberg AK, Scheede-Bergdahl C, Doessing S, Kjaer A, Kjaer M, Boushel R. Nitric oxide and prostaglandins influence local skeletal muscle blood flow during exercise in humans: coupling between local substrate uptake and blood flow. Am J Physiol Regul Integr Comp Physiol. 291: R803-R809, 2006. [IF 3.168]
30. Laaksonen MS, Kyrolainen H, Kalliokoski KK, Nuutila P, Knuuti J. The association between muscle EMG and perfusion in knee extensor muscles. Clin Physiol Funct Imaging. 26: 99-105, 2006. [IF 1.869]
29. Hannukainen J, Kalliokoski KK, Nuutila P, Fujimoto T, Kemppainen J, Viljanen T, Laaksonen MS, Parkkola R, Knuuti J, Kjaer M. In vivo measurements of glucose uptake in human Achilles tendon during different exercise intensities. Int J Sports Med. 26: 727-731, 2005. [IF 2.528]
28. Kemppainen J, Aalto S, Fujimoto T, Kalliokoski KK, Langsjo J, Oikonen V, Rinne J, Nuutila P, Knuuti J. High intensity exercise decreases global brain glucose uptake in humans. J Physiol. 568: 323-332, 2005. [IF 4.731]
27. Kalliokoski RJ, Kalliokoski KK, Sundell J, Engblom E, Penttinen M, Kantola I, Raitakari OT, Knuuti J, Nuutila P. Impaired myocardial perfusion reserve but preserved peripheral endothelial function in patients with Fabry disease. J Inherit Metab Dis. 28: 563-573, 2005. [IF 3.541]
26. Kalliokoski KK, Langberg H, Ryberg AK, Scheede-Bergdahl C, Doessing S, Kjaer A, Boushel R, Kjaer M. The effect of dynamic knee-extension exercise on patellar tendon and quadriceps femoris muscle glucose uptake in humans studied by positron emission tomography. J Appl Physiol. 99: 1189-1192, 2005. [IF 3.004]
25. Hannukainen JC, Kujala UM, Toikka J, Heinonen OJ, Kapanen J, Vahlberg T, Kaprio J, Kalliokoski KK. Cardiac structure and function in monozygotic twin pairs discordant for physical fitness. J Appl Physiol. 99: 535-541, 2005. [IF 3.004]
24. Kalliokoski KK, Knuuti J, Nuutila P. Relationship between muscle blood flow and oxygen uptake during exercise in endurance-trained and untrained men. J Appl Physiol. 98: 380-383, 2005. [IF 3.004]
23. Kalliokoski KK, Laaksonen MS, Luotolahti M, Laine H, Takala TO, Nuutila P, Knuuti J. Myocardial perfusion after marathon running. Scand J Med Sci Sports. 14: 208-214, 2004. [IF 3.025]
22. Stolen KQ, Kemppainen J, Kalliokoski KK, Hallsten K, Luotolahti M, Karanko H, Lehikoinen P, Viljanen T, Salo T, Airaksinen KE, Nuutila P, Knuuti J. Myocardial perfusion reserve and oxidative metabolism contribute to exercise capacity in patients with dilated cardiomyopathy. J Card Fail. 10: 132-140, 2004. [IF 3.259]
21. Kalliokoski KK, Knuuti J, Nuutila P. Blood transit time heterogeneity is associated to oxygen extraction in exercising human skeletal muscle. Microvasc Res. 67: 125-132, 2004. [IF 2.3]
20. Stolen KQ, Kemppainen J, Kalliokoski KK, Karanko H, Toikka J, Janatuinen T, Raitakari OT, Airaksinen KE, Nuutila P, Knuuti J. Myocardial perfusion reserve and peripheral endothelial function in patients with idiopathic dilated cardiomyopathy. Am J Cardiol. 93: 64-68, 2004. [IF 3.154]
19. Stolen KQ, Kemppainen J, Kalliokoski KK, Luotolahti M, Viljanen T, Nuutila P, Knuuti J. Exercise training improves insulin-stimulated myocardial glucose uptake in patients with dilated cardiomyopathy. J Nucl Cardiol. 10: 447-455, 2003. [IF 2.929]
18. Kemppainen J, Stolen K, Kalliokoski KK, Salo T, Karanko H, Viljanen T, Airaksinen J, Nuutila P, Knuuti J. Exercise training improves insulin stimulated skeletal muscle glucose uptake independent of changes in perfusion in patients with dilated cardiomyopathy. J Card Fail. 9: 286-295, 2003. [IF 3.259]
17. Kalliokoski KK, Laaksonen MS, Knuuti J, Nuutila P. Perfusion distribution between and within muscles during intermittent static exercise in endurance-trained and untrained men. Int J Sports Med. 24: 400-403, 2003. [IF 2.528]
16. Fujimoto T, Kemppainen J, Kalliokoski KK, Nuutila P, Ito M, Knuuti J. Skeletal muscle glucose uptake response to exercise in trained and untrained men. Med Sci Sports Exerc. 35: 777-783, 2003. [IF 4.041]
15. Sundell J, Laine H, Luotolahti M, Nuutila P, Kalliokoski K, Raitakari O, Knuuti J. Blunted coronary vasoreactivity to insulin is an early alteration in hypertension. J Vasc Res . 40: 58-67, 2003. [IF 2.186]
14. Stolen KQ, Kemppainen J, Ukkonen H, Kalliokoski KK, Luotolahti M, Lehikoinen P, Hamalainen H, Salo T, Airaksinen KE, Nuutila P, Knuuti J. Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopathy. J Am Coll Cardiol. 41: 460-467, 2003. [IF 17.759]
13. Kalliokoski KK, Kuusela TA, Laaksonen MS, Knuuti J, Nuutila P. Muscle fractal vascular branching pattern and microvascular perfusion heterogeneity in endurance-trained and untrained men. J Physiol. 546: 529-535, 2003. [IF 4.731]
12. Laaksonen MS, Kalliokoski KK, Kyrolainen H, Kemppainen J, Teras M, Sipila H, Nuutila P, Knuuti J. Skeletal muscle blood flow and flow heterogeneity during dynamic and isometric exercise in humans. Am J Physiol Heart Circ Physiol. 284: H979-H986, 2003. [IF 3.324]
11. Kalliokoski KK, Laaksonen MS, Takala TO, Knuuti J, Nuutila P. Muscle oxygen extraction and perfusion heterogeneity during continuous and intermittent static exercise. J Appl Physiol. 94: 953-958, 2003. [IF 3.004]
10. Kemppainen J, Fujimoto T, Kalliokoski KK, Viljanen T, Nuutila P, Knuuti J. Myocardial and skeletal muscle glucose uptake during exercise in humans. J Physiol. 542: 403-412, 2002. [IF 4.731]
9. Sundell J, Laine H, Luotolahti M, Kalliokoski K, Raitakari O, Nuutila P, Knuuti J. Obesity affects myocardial vasoreactivity and coronary flow response to insulin. Obes Res. 10: 617-624, 2002. [IF 3.614]
8. Kalliokoski KK, Nuutila P, Laine H, Luotolahti M, Janatuinen T, Raitakari OT, Takala TO, Knuuti J. Myocardial perfusion and perfusion reserve in endurance-trained men. Med Sci Sports Exerc. 34: 948-953, 2002. [IF 4.041]
7. Sundell J, Nuutila P, Laine H, Luotolahti M, Kalliokoski K, Raitakari O, Knuuti J. Dose-dependent vasodilating effects of insulin on adenosine-stimulated myocardial blood flow. Diabetes. 51: 1125-1130, 2002. [IF 8.784]
6. Peltoniemi P, Yki-Jarvinen H, Laine H, Oikonen V, Ronnemaa T, Kalliokoski K, Raitakari O, Knuuti MJ, Nuutila P. Evidence for spatial heterogeneity in insulin- and exercise-induced increases in glucose uptake: studies in normal subjects and patients with type 1 diabetes. J Clin Endocrinol Metab. 86: 5525-5533, 2001. [IF 5.531]
5. Lehtio K, Oikonen V, Gronroos T, Eskola O, Kalliokoski K, Bergman J, Solin O, Grenman R, Nuutila P, Minn H. Imaging of blood flow and hypoxia in head and neck cancer: initial evaluation with [(15)O]H(2)O and [(18)F]fluoroerythronitroimidazole PET. J Nucl Med . 42: 1643-1652, 2001. [IF 5.849]
4. Kalliokoski KK, Kuusela TA, Nuutila P, Tolvanen T, Oikonen V, Teras M, Takala TE, Knuuti J. Perfusion heterogeneity in human skeletal muscle: fractal analysis of PET data. Eur J Nucl Med . 28: 450-456, 2001. [IF 5.537]
3. Kalliokoski KK, Oikonen V, Takala TO, Sipila H, Knuuti J, Nuutila P. Enhanced oxygen extraction and reduced flow heterogeneity in exercising muscle in endurance-trained men. Am J Physiol Endocrinol Metab. 280: E1015-E1021, 2001. [IF 3.825]
2. Kalliokoski KK, Kemppainen J, Larmola K, Takala TO, Peltoniemi P, Oksanen A, Ruotsalainen U, Cobelli C, Knuuti J, Nuutila P. Muscle blood flow and flow heterogeneity during exercise studied with positron emission tomography in humans. Eur J Appl Physiol. 83: 395-401, 2000. [IF 2.328]
1. Nuutila P, Kalliokoski K. Use of positron emission tomography in the assessment of skeletal muscle and tendon metabolism and perfusion. Scand J Med Sci Sports. 10: 346-350, 2000. [IF 3.025]
Updated Jan 25, 2022